ARG22189
anti-IL7 antibody [BVD10-11C10] (Biotin)
anti-IL7 antibody [BVD10-11C10] (Biotin) for ELISA and Human
Overview
| Product Description | Biotin-conjugated Rat Monoclonal antibody [BVD10-11C10] recognizes IL7 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | Human IL-7 |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | BVD10-11C10 |
| Isotype | IgG2a, kappa |
| Target Name | IL7 |
| Antigen Species | Human |
| Immunogen | E. coli-expressed Human IL-7 |
| Conjugation | Biotin |
| Alternate Names | IL-7; Interleukin-7 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS and 0.1% Sodium azide. |
| Preservative | 0.1% Sodium azide |
| Concentration | 0.5 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | IL7 |
| Gene Full Name | interleukin 7 |
| Background | The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010] |
| Function | Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. [UniProt] |
| Calculated MW | 20 kDa |
