ARG44453
anti-IMPAD1 antibody
anti-IMPAD1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IMPAD1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IMPAD1 |
| Antigen Species | Human |
| Immunogen | Human IMPAD1 recombinant protein |
| Conjugation | Un-conjugated |
| Alternate Names | BPNT2; 3'(2'), 5'-Bisphosphate Nucleotidase 2; IMPA3; GPAPP; Golgi-Resident Adenosine 3',5'-Bisphosphate 3'-Phosphatase; IMPAD1; Inositol Monophosphatase Domain-Containing Protein 1; Inositol Monophosphatase Domain Containing 1; Phosphoadenosine Phosphate 3'-Nucleotidase; Golgi-Resident Nucleotide Phosphatase; Myo-Inositol Monophosphatase A3; Golgi-Resident PAP Phosphatase |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | BPNT2 |
| Gene Full Name | 3'(2'), 5'-Bisphosphate Nucleotidase 2 |
| Background | This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. |
| Function | Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I1P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4. |
| Cellular Localization | Golgi apparatus, Membrane |
| Calculated MW | 39 kDa |
| PTM | Acetylation, Glycoprotein |
