ARG58871

anti-ING1 antibody

anti-ING1 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes ING1
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ING1
Antigen Species Human
Immunogen Synthetic peptide of Human ING1.
Conjugation Un-conjugated
Alternate Names p47ING1a; p24ING1c; Inhibitor of growth protein 1; p33ING1b; p33ING1; p47; p33

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat brain
Observed Size 47 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3621 Human ING1

Swiss-port # Q9UK53 Human Inhibitor of growth protein 1

Gene Symbol ING1
Gene Full Name inhibitor of growth family, member 1
Background This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Function Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 47 kDa