ARG42906

anti-INMT / TEMT antibody

anti-INMT / TEMT antibody for Western blot,ICC/IF and Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes INMT / TEMT
Tested Reactivity Ms
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name INMT / TEMT
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-263 of Human INMT / TEMT (NP_006765.4).
Conjugation Un-conjugated
Alternate Names Thioether S-methyltransferase; TEMT; Indolamine N-methyltransferase; EC 2.1.1.96; Indolethylamine N-methyltransferase; Aromatic alkylamine N-methyltransferase; Arylamine N-methyltransferase; Amine N-methyltransferase; EC 2.1.1.49

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse lung
Observed Size ~ 30 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 21743 Mouse INMT

Swiss-port # P40936 Mouse Indolethylamine N-methyltransferase

Gene Symbol INMT
Gene Full Name indolethylamine N-methyltransferase
Background N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream MINDY4 (aka FAM188B) gene. In rodents and other mammals such as cetartiodactyla this gene is in the opposite orientation compared to its orientation in human and other primates and this gene appears to have been lost in carnivora and chiroptera. [provided by RefSeq, Jul 2019]
Function Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds (By similarity). Catalyzes the N-methylation of tryptamine and structurally related compounds. [UniProt]
Cellular Localization Cytoplasm. [UniProt]
Calculated MW 29 kDa