ARG40358

anti-INSRR / IRR (beta chain) antibody

anti-INSRR / IRR (beta chain) antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes INSRR / IRR (beta chain)
Tested Reactivity Hu
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name INSRR / IRR (beta chain)
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 668-702 of Human INSRR.
Conjugation Un-conjugated
Alternate Names Insulin receptor-related protein; IRR; EC 2.7.10.1; IR-related receptor; Insulin Receptor R

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:25
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3645 Human INSRR

Swiss-port # P14616 Human Insulin receptor-related protein

Gene Symbol INSRR
Gene Full Name insulin receptor-related receptor
Function Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 144 kDa
PTM Autophosphorylated on tyrosine residues between pH 7.9 and pH 10.5. [UniProt]