ARG40362

anti-ITIH1 antibody

anti-ITIH1 antibody for Western blot,Flow cytometry and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes ITIH1
Tested Reactivity Hu
Tested Application FACS, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ITIH1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide between aa. 606-635 of Human ITIH1.
Conjugation Un-conjugated
Alternate Names ITIH; Inter-alpha-trypsin inhibitor complex component III; SHAP; Inter-alpha-inhibitor heavy chain 1; Serum-derived hyaluronan-associated protein; H1P; ITI-HC1; Inter-alpha-trypsin inhibitor heavy chain H1; IATIH; ITI heavy chain H1; IGHEP1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:10 - 1:50
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human plasma

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3697 Human ITIH1

Swiss-port # P19827 Human Inter-alpha-trypsin inhibitor heavy chain H1

Gene Symbol ITIH1
Gene Full Name inter-alpha-trypsin inhibitor heavy chain 1
Background The protein encoded by this gene is the heavy chain of a serine protease inhibitor that may serve to carry hyaluronan in plasma. This gene is part of a cluster of similar genes on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Function May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.

Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 101 kDa
PTM Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.

The S-linked glycan is composed of two 6-carbon sugars, possibly Glc or Gal. [UniProt]