ARG44357
anti-ITIH3 antibody
anti-ITIH3 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ITIH3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ITIH3 |
| Antigen Species | Human |
| Immunogen | Human ITIH3 recombinant fusion protein (a.a. sequence: 35-180). |
| Conjugation | Un-conjugated |
| Alternate Names | ITIH3; Inter-Alpha-Trypsin Inhibitor Heavy Chain 3; Inter-Alpha-Trypsin Inhibitor Heavy Chain H3; H3P; Inter-Alpha (Globulin) Inhibitor, H3 Polypeptide; Pre-Alpha (Globulin) Inhibitor, H3 Polypeptide; Serum-Derived Hyaluronan-Associated Protein; Inter-Alpha (Globulin) Inhibitor H3; Inter-Alpha-Inhibitor Heavy Chain 3; ITI Heavy Chain H3; ITI-HC3; SHAP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.01% Thimerosal and 50% Glycerol. |
| Preservative | 0.01% Thimerosal |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ITIH3 |
| Gene Full Name | Inter-Alpha-Trypsin Inhibitor Heavy Chain 3 |
| Background | This gene encodes the heavy chain subunit of the pre-alpha-trypsin inhibitor complex. This complex may stabilize the extracellular matrix through its ability to bind hyaluronic acid. Polymorphisms of this gene may be associated with increased risk for schizophrenia and major depressive disorder. This gene is present in an inter-alpha-trypsin inhibitor family gene cluster on chromosome 3. |
| Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. |
| Cellular Localization | Secreted |
| Calculated MW | 100 kDa |
| PTM | Glycoprotein, Proteoglycan |
