ARG63029
anti-IgA antibody [AD3]
anti-IgA antibody [AD3] for ELISA,IHC-Formalin-fixed paraffin-embedded sections and Human
Cancer antibody; Developmental Biology antibody; Immune System antibody
Overview
Product Description | Mouse Monoclonal antibody [AD3] recognizes IgA |
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Tested Reactivity | Hu |
Tested Application | ELISA, IHC-P |
Specificity | The clone AD3 reacts with alpha-chain of human IgA1 and IgA2. |
Host | Mouse |
Clonality | Monoclonal |
Clone | AD3 |
Isotype | IgG1 |
Target Name | IgA |
Antigen Species | Human |
Immunogen | Purified human IgA. |
Conjugation | Un-conjugated |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | IHC-P: Colon |
Properties
Form | Liquid |
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Purification | Purified from ascites by precipitation methods and ion exchange chromatography. |
Purity | > 95% (by SDS-PAGE) |
Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
Preservative | 15 mM Sodium azide |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Background | Immunoglobulin A (IgA) is the major immunoglobulin class in body secretions that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract. Its serum concentration is approximately 0.2 g/l and biological survival (T1/2 in plasma) 6 days. Plasma IgA is predominantly monomeric (160 kDa) and of the IgA1 subclass, and is mostly produced in the bone marrow. Over half of IgA produced by the intestinal lamina propria plasmocytes is in oligomeric form and 35% of it is IgA2. |
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Research Area | Cancer antibody; Developmental Biology antibody; Immune System antibody |