ARG65480
anti-IgM antibody [MA2]
anti-IgM antibody [MA2] for ELISA and Human
Cell Biology and Cellular Response antibody; Developmental Biology antibody; Immune System antibody
Overview
| Product Description | Mouse Monoclonal antibody [MA2] recognizes IgM |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | The clone MA2 reacts with µ-chain of human IgM, Fab - region localized epitope. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | MA2 |
| Isotype | IgG2b |
| Target Name | IgM |
| Antigen Species | Human |
| Immunogen | IgM from human serum._x000D_ |
| Conjugation | Un-conjugated |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from ascites by precipitation methods and ion exchange chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | TBS (pH 8.0) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Background | Immunoglobulin M (IgM) is produced as a 900 kDa pentamer, which is an efficient complement binder. This antibody type is produced initially in the immune response and it is the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. IgM concentration in blood is 0.12 g/l and its biological survival (plasma T1/2) is 5 days. |
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| Research Area | Cell Biology and Cellular Response antibody; Developmental Biology antibody; Immune System antibody |
