ARG59896
anti-KCND1 / Kv4.1 antibody
anti-KCND1 / Kv4.1 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes KCND1 / Kv4.1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | KCND1 / Kv4.1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein corresponding to T442-L647 of Human KCND1 / Kv4.1. |
| Conjugation | Un-conjugated |
| Alternate Names | KV4.1; Potassium voltage-gated channel subfamily D member 1; Voltage-gated potassium channel subunit Kv4.1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q03719 Mouse Potassium voltage-gated channel subfamily D member 1 Swiss-port # Q9NSA2 Human Potassium voltage-gated channel subfamily D member 1 |
|---|---|
| Gene Symbol | KCND1 |
| Gene Full Name | potassium channel, voltage gated Shal related subfamily D, member 1 |
| Background | This gene encodes a multipass membrane protein that comprises the pore subunit of the voltage-gated A-type potassium channel, which functions in the repolarization of membrane action potentials. Activity of voltage-gated potassium channels is important in a number of physiological processes, among them the regulation of neurotransmitter release, heart rate, insulin secretion, and smooth muscle contraction. [provided by RefSeq, Aug 2013] |
| Function | Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. [UniProt] |
| Cellular Localization | Membrane; Multi-pass membrane protein. Cell projection, dendrite. [UniProt] |
| Calculated MW | Isoform 1: 71 kDa Isoform 2: 29 kDa |
