ARG59552

anti-KDM6B / JMJD3 antibody

anti-KDM6B / JMJD3 antibody for Western blot,ICC/IF and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes KDM6B / JMJD3
Tested Reactivity Hu
Predict Reactivity Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name KDM6B / JMJD3
Antigen Species Human
Immunogen A 16 aa peptide within aa. 1370 - 1420 of Human KDM6B / JMJD3.
Conjugation Un-conjugated
Alternate Names JmjC domain-containing protein 3; Lysine-specific demethylase 6B; JMJD3; Lysine demethylase 6B; Jumonji domain-containing protein 3; EC 1.14.11.-

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF2.5 - 5 µg/ml
WB0.5 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control K562 Cell Lysate

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS and 0.02% Sodium azide
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 23135 Human KDM6B

Swiss-port # O15054 Human Lysine-specific demethylase 6B

Gene Symbol KDM6B
Gene Full Name lysine (K)-specific demethylase 6B
Function Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 177 kDa