ARG44293
anti-KLF13 antibody
anti-KLF13 antibody for Western blot and Human,Mouse
Overview
Product Description | Rabbit Polyclonal antibody recognizes KLF13 |
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Tested Reactivity | Hu, Ms |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | KLF13 |
Antigen Species | Human |
Immunogen | Synthetic peptide |
Conjugation | Un-conjugated |
Alternate Names | KLF13; KLF Transcription Factor 13; RFLAT-1; BTEB3; NSLP1; Novel Sp1-Like Zinc Finger Transcription Factor 1; Transcription Factor BTEB3; Transcription Factor NSLP1; Krueppel-Like Factor 13 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Antigen Affinity Purified |
Buffer | PBS with 0.02% Sodium azide |
Preservative | 0.02% Sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | KLF13 |
Gene Full Name | KLF Transcription Factor 13 |
Background | KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]). |
Function | Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells. |
Cellular Localization | Nucleus |
Calculated MW | 31 kDa |
PTM | Phosphoprotein |