ARG54000
anti-KLF4 antibody
anti-KLF4 antibody for Western blot and Mouse
Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Gene Regulation antibody
Overview
| Product Description | Mouse Monoclonal antibody recognizes KLF4 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Target Name | KLF4 |
| Antigen Species | Mouse |
| Immunogen | Purified recombinant mouse KLF4 protein fragments expressed in E.coli. |
| Conjugation | Un-conjugated |
| Alternate Names | GKLF; EZF; Epithelial zinc finger protein EZF; Krueppel-like factor 4; Gut-enriched krueppel-like factor |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 55/65 kDa |
Properties
| Form | Liquid |
|---|---|
| Buffer | Ascites |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Klf4 |
| Gene Full Name | Kruppel-like factor 4 (gut) |
| Background | Transcription factor; can act both as activator and as repressor.Binds the 5'-CACCC-3' core sequence.Binds to the promoter region of its own gene and can activate its own transcription.Regulates the expression of key transcription factors during embryonic development.Plays an important role in maintaining embryonic stem cells,and in preventing their differentiation.Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface.Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.Contributes to the down-regulation of p53/TP53 transcription. |
| Function | Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity). [UniProt] |
| Cellular Localization | Nucleus. |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Gene Regulation antibody |
| Calculated MW | 55 kDa |
