ARG20564
anti-Kv4.3 antibody
anti-Kv4.3 antibody for Western blot and Mouse
Cell Biology and Cellular Response antibody; Neuroscience antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Kv4.3 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Specificity | This antibody is reactive to the 74 kDa mouse Kv4.3 in mouse brain tissue extract on Western blot. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Kv4.3 |
| Antigen Species | Mouse |
| Immunogen | KLH-conjugated synthetic peptide around aa. 55-64 of Mouse voltage-gated potassium channel Kv4.3. (RTTLERYPDT) |
| Conjugation | Un-conjugated |
| Alternate Names | Kv4.3; KV4.3; Potassium voltage-gated channel subfamily D member 3; Kncd3; AW045978; KCND3S; BRGDA9; SCA19; KSHIVB; SCA22; Voltage-gated potassium channel subunit Kv4.3; KCND3L |
Application Instructions
| Application Suggestion |
|
|---|
Properties
| Form | Powder |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | Lyophilized in 0.01M PBS (pH 7.4) |
| Reconstitution | 100 μl of double distilled water is recommended to adjust the final concentration to 1.0 mg/ml. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9Z0V1 Mouse Potassium voltage-gated channel subfamily D member 3 |
|---|---|
| Gene Symbol | Kcnd3 |
| Gene Full Name | potassium voltage-gated channel, Shal-related family, member 3 |
| Background | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq, Jul 2008] |
| Function | Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Neuroscience antibody |
| Calculated MW | 73 kDa |
| PTM | Regulated through phosphorylation at Ser-569 by CaMK2D. |
