ARG66173

anti-LALBA / Lactalbumin antibody

anti-LALBA / Lactalbumin antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Mouse Monoclonal antibody recognizes LALBA / Lactalbumin
Tested Reactivity Hu
Tested Application IHC-P, WB
Specificity The antibody detects endogenous alpha Lactalbumin proteins.
Host Mouse
Clonality Monoclonal
Target Name LALBA / Lactalbumin
Antigen Species Human
Immunogen Synthetic peptide of Human LALBA / Lactalbumin.
Conjugation Un-conjugated
Alternate Names Lactose synthase B protein; Alpha-lactalbumin; Lysozyme-like protein 7

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:300
WB1:1000
Application Note IHC-P: Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0) for 20 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3906 Human LALBA

Swiss-port # P00709 Human Alpha-lactalbumin

Gene Symbol LALBA
Gene Full Name lactalbumin, alpha-
Background This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008]
Function Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins. [UniProt]
Calculated MW 16 kDa