ARG58828

anti-LIFR antibody

anti-LIFR antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes LIFR
Tested Reactivity Hu
Predict Reactivity Bov
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name LIFR
Antigen Species Human
Immunogen Synthetic peptide corresponding to aa. 863-899 of Human LIFR (EWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLE).
Conjugation Un-conjugated
Alternate Names CD118; CD antigen CD118; STWS; SJS2; LIF receptor; Leukemia inhibitory factor receptor; SWS; LIF-R

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.1 - 0.5 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA.
Preservative 0.05% Sodium azide
Stabilizer 5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3977 Human LIFR

Swiss-port # P42702 Human Leukemia inhibitory factor receptor

Gene Symbol LIFR
Gene Full Name leukemia inhibitory factor receptor alpha
Background This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Function Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells. [UniProt]
Cellular Localization Isoform 1: Cell membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 124 kDa