ARG53248
anti-LMO2 antibody [SP51]
anti-LMO2 antibody [SP51] for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cell Biology and Cellular Response antibody
Overview
| Product Description | Rabbit Monoclonal antibody [SP51] recognizes LMO2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SP51 |
| Isotype | IgG |
| Target Name | LMO2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to near N-terminus of human LMO2 protein. |
| Conjugation | Un-conjugated |
| Alternate Names | RHOM2; LMO-2; TTG2; LIM domain only protein 2; T-cell translocation protein 2; RBTN2; Rhombotin-2; Cysteine-rich protein TTG-2; RBTNL1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Incubation Time: 30 min at RT. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Positive Control | Hodgkin's Lymphoma, Tonsil, Ramos |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by protein A/G |
| Buffer | PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide |
| Preservative | < 0.1% Sodium azide |
| Stabilizer | 1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | LMO2 encodes a cysteine-rich, two LIM-doman protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where T-cell acute lymphoblastic leukemia-specific translocations occur. |
| Cellular Localization | Nucleus |
| Research Area | Cell Biology and Cellular Response antibody |
| Calculated MW | 18 kDa |
