ARG40953
anti-LMX1B antibody
anti-LMX1B antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LMX1B |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LMX1B |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within aa. 1-100 of Human LMX1B (NP_001167618.1). |
| Conjugation | Un-conjugated |
| Alternate Names | NPS1; LMX1.2; LIM/homeobox protein 1.2; LIM homeobox transcription factor 1-beta; LIM/homeobox protein LMX1B; LMX-1.2 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O60663 Human LIM homeobox transcription factor 1-beta Swiss-port # O88609 Mouse LIM homeobox transcription factor 1-beta |
|---|---|
| Gene Symbol | LMX1B |
| Gene Full Name | LIM homeobox transcription factor 1, beta |
| Background | This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
| Function | Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 45 kDa |
