ARG56522
anti-LPAR1 / EDG2 antibody
anti-LPAR1 / EDG2 antibody for ICC/IF,Western blot and Human,Mouse,Rat,Bovine,Sheep
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LPAR1 / EDG2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Bov, Sheep |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LPAR1 / EDG2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around aa. 342-359 of Human LPAR1 / EDG2. (DRSASSLNHTILAGVHSN) |
| Conjugation | Un-conjugated |
| Alternate Names | Gpcr26; LPA receptor 1; LPA1; rec.1.3; EDG2; edg-2; Lysophosphatidic acid receptor 1; Lysophosphatidic acid receptor Edg-2; Mrec1.3; vzg-1; VZG1; LPA-1; GPR26 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LPAR1 |
| Gene Full Name | lysophosphatidic acid receptor 1 |
| Background | The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008] |
| Function | Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation. [UniProt] |
| Calculated MW | 41 kDa |
| PTM | N-glycosylated. |
