ARG44411
anti-LRCH4 antibody
anti-LRCH4 antibody for Flow cytometry,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LRCH4 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LRCH4 |
| Antigen Species | Human |
| Immunogen | Human LRCH4 recombinant protein (aa. sequence: K256-R580). |
| Conjugation | Un-conjugated |
| Alternate Names | LRCH4; Leucine Rich Repeats And Calponin Homology Domain Containing 4; LRRN1; LRN; Leucine-Rich Repeat And Calponin Homology Domain-Containing Protein 4; Leucine-Rich Repeats And Calponin Homology (CH) Domain Containing 4; Leucine-Rich Neuronal Protein |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O75427 Human Leucine-rich repeat and calponin homology domain-containing protein 4 Swiss-port # Q921G6 Mouse Leucine-rich repeat and calponin homology domain-containing protein 4 |
|---|---|
| Gene Symbol | LRCH4 |
| Gene Full Name | Leucine Rich Repeats And Calponin Homology Domain Containing 4 |
| Background | This gene encodes a protein that contains leucine-rich repeats (LRR) at its amino terminus and that is known to be involved in ligand binding. The carboxyl terminus may act as a membrane anchor. Identified structural elements suggest that the encoded protein resembles a receptor. |
| Function | Accessory protein that regulates signaling by multiple TLRs, acting as a broad-spanning regulator of the innate immune response. In macrophages, binds LPS and promotes proper docking of LPS in lipid raft membrane. May be required for lipid raft maintenance. |
| Cellular Localization | Cell membrane, Membrane |
| Calculated MW | 73 kDa |
| PTM | Phosphoprotein |
