ARG44413
anti-LRIT3 antibody
anti-LRIT3 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LRIT3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LRIT3 |
| Antigen Species | Human |
| Immunogen | Human LRIT3 recombinant protein (aa. sequence: E50-R573). |
| Conjugation | Un-conjugated |
| Alternate Names | LRIT3; Leucine Rich Repeat, Ig-Like And Transmembrane Domains 3; FIGLER4; CSNB1F; Leucine-Rich Repeat, Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 3; Fibronectin Type III, Immunoglobulin And Leucine Rich Repeat Domains 4 |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q3SXY7 Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-c |
|---|---|
| Gene Symbol | LRIT3 |
| Gene Full Name | Leucine Rich Repeat, Ig-Like And Transmembrane Domains 3 |
| Background | This gene encodes a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F. |
| Function | Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells. |
| Cellular Localization | Cell projection, Endoplasmic reticulum, Membrane |
| Calculated MW | 75 kDa |
| PTM | Disulfide bond, Glycoprotein |
