ARG41340
anti-LRRC4 antibody
anti-LRRC4 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LRRC4 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LRRC4 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 544-653 of Human LRRC4 (NP_071426.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Netrin-G2 ligand; Leucine-rich repeat-containing protein 4; Nasopharyngeal carcinoma-associated gene 14 protein; NAG14; Brain tumor-associated protein BAG; NGL-2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | U-87 MG | ||||
| Observed Size | 80 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LRRC4 |
| Gene Full Name | leucine rich repeat containing 4 |
| Background | This gene is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown. [provided by RefSeq, Jul 2008] |
| Function | Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity). [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=LRRC4 and DLG4 are interdependent for synaptic localization. [UniProt] |
| Calculated MW | 73 kDa |
| PTM | N-glycosylated. [UniProt] |
