ARG44429

anti-LSG1 antibody

anti-LSG1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes LSG1
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name LSG1
Antigen Species Human
Immunogen Human LSG1 recombinant protein (aa. sequence: D73-D578).
Conjugation Un-conjugated
Alternate Names LSG1; Large 60S Subunit Nuclear Export GTPase 1; Large Subunit GTPase 1 Homolog; FLJ11301; HLsg1,; Large Subunit GTPase 1 Homolog (S. Cerevisiae)

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1-3 µg/1x10^6 cells
ICC/IF5 µg/ml
IHC-P2-5 µg/ml
WB0.25-0.5 µg/ml
Application Note The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
Preservative 0.05% Sodium azide
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

Bioinformation

Database Links

GeneID: 224092 Mouse LSG1

GeneID: 288029 Rat LSG1

GeneID: 55341 Human LSG1

Gene Symbol LSG1
Gene Full Name Large 60S Subunit Nuclear Export GTPase 1
Background This gene encodes a protein related to the yeast large subunit GTPase 1. The encoded protein is necessary for cell viability and may localize in the endoplasmic reticulum, nucleus and cytoplasm.
Function GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable).
Cellular Localization Cytoplasm, Endoplasmic reticulum, Nucleus
Calculated MW 75 kDa
PTM Phosphoprotein