ARG44574
anti-LYAR antibody
anti-LYAR antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LYAR |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LYAR |
| Antigen Species | Human |
| Immunogen | Human LYAR recombinant protein (aa. sequence: M1-K379). |
| Conjugation | Un-conjugated |
| Alternate Names | LYAR; Ly1 Antibody Reactive; Cell Growth-Regulating Nucleolar Protein; ZC2HC2; ZLYAR; Ly1 Antibody Reactive Homolog (Mouse); Ly1 Antibody Reactive Homolog |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Preservative | 4% Trehalose |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LYAR |
| Gene Full Name | Ly1 Antibody Reactive |
| Background | Enables several functions, including DNA-binding transcription factor binding activity; identical protein binding activity; and transcription regulator inhibitor activity. Involved in several processes, including erythrocyte development; negative regulation of innate immune response; and regulation of transcription, DNA-templated. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Prevents nucleolin/NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal. [Uniprot] |
| Cellular Localization | Cell projection, Cytoplasm, Nucleus. [Uniprot] |
| Calculated MW | 44 kDa |
| PTM | Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot] |
