ARG67137
anti-Lamin B1 antibody
anti-Lamin B1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody; Signaling Transduction antibody; NRF-2 Nuclear Localization Study antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Lamin B1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Lamin B1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human Lamin B1 |
| Conjugation | Un-conjugated |
| Alternate Names | LMNB1; Lamin B1; Lamin-B1; LMN2; LMNB; MCPH26; ADLD; LMN |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.02% Sodium azide, 0.5% BSA and 50% Glycerol |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA, 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LMNB1 |
| Gene Full Name | lamin B1 |
| Background | This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
| Function | The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively. [UniProt] |
| Cellular Localization | Intermediate filament, Nucleus. [UniProt] |
| Highlight | Related products: Lamin B1 antibodies; Lamin B1 Duos / Panels; |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody; Signaling Transduction antibody; NRF-2 Nuclear Localization Study antibody |
| Calculated MW | 66 kDa |
| PTM | Acetylation, Disulfide bond, Glycoprotein, Isopeptide bond, Lipoprotein, Methylation, Phosphoprotein, Prenylation, Ubl conjugation. [UniProt] |
