ARG24022
anti-Laminin antibody
anti-Laminin antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Laminin |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA, ICC/IF, IHC-P |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Laminin |
| Antigen Species | Mouse |
| Immunogen | Laminin extracted from Mouse EHS tumor tissues. |
| Conjugation | Un-conjugated |
| Alternate Names | S-LAM-alpha; LAMA; Laminin-1 subunit alpha; PTBHS; Laminin-3 subunit alpha; S-LAM alpha; S-laminin subunit alpha; Laminin A chain; Laminin subunit alpha-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LAMA1 |
| Gene Full Name | laminin, alpha 1 |
| Background | This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014] |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. [UniProt] |
| Calculated MW | 337 kDa |
| PTM | Tyrosine phosphorylated by PKDCC/VLK. [UniProt] |
