ARG58858

anti-Lumican antibody

anti-Lumican antibody for Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes Lumican
Tested Reactivity Hu, Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Lumican
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 19-338 of Human Lumican (NP_002336.1).
Conjugation Un-conjugated
Alternate Names LDC; Keratan sulfate proteoglycan lumican; Lumican; SLRR2D; KSPG lumican

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse heart
Observed Size 48 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17022 Mouse LUM

GeneID: 4060 Human LUM

Swiss-port # P51884 Human Lumican

Swiss-port # P51885 Mouse Lumican

Gene Symbol LUM
Gene Full Name lumican
Background This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]
Cellular Localization Secreted, extracellular space, extracellular matrix. [UniProt]
Calculated MW 38 kDa
PTM Sulfated on tyrosine residue(s). [UniProt]