ARG41093
anti-Ly6G antibody [1A8] (low endotoxin)
anti-Ly6G antibody [1A8] (low endotoxin) for Flow cytometry,Functional study,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Mouse
Mouse Inflammatory Cell Marker antibody; Neurophil Marker antibody; Mouse MDSC Marker antibody; Myeloid-derived suppressor cell antibody
Overview
| Product Description | Low endotoxin Rat Monoclonal antibody [1A8] recognizes Ly6G |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS, FuncSt, IHC-P, IP |
| Specificity | The antibody specifically reacts with the 21-25 kDa glycophosphatidylinositol-anchored protein known as Ly6G, expressed by the granulocytes from the bone marrow and periphery neutrophils. |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 1A8 |
| Isotype | IgG2a, kappa |
| Target Name | Ly6G |
| Antigen Species | Mouse |
| Immunogen | Mouse Ly6G |
| Conjugation | Un-conjugated |
| Alternate Names | Gr1; Gr-1; Ly-6G |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Purification Note | Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. |
| Buffer | PBS (pH 7.2) |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Ly6g |
| Gene Full Name | lymphocyte antigen 6 complex, locus G |
| Background | Ly6G is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. Ly6G is a good marker for detection of peripheral neutrophils. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Physiological role of Ly6G remains still unclear. Its treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses. _x000D_ |
| Cellular Localization | Cell membrane; GPI-anchor. [UniProt] |
| Highlight | Related products: Ly6 antibodies; Ly6 ELISA Kits; Ly6 Duos / Panels; Anti-Rat IgG secondary antibodies; Related news: New antibody panels and duos for Tumor immune microenvironment Exploring Antiviral Immune Response |
| Research Area | Mouse Inflammatory Cell Marker antibody; Neurophil Marker antibody; Mouse MDSC Marker antibody; Myeloid-derived suppressor cell antibody |
| Calculated MW | 12 kDa |
