ARG10825

anti-MAG antibody

anti-MAG antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description

Rabbit Polyclonal antibody recognizes MAG

Tested Reactivity Hu, Ms, Rat
Predict Reactivity Dog, Mk, Rb
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MAG
Antigen Species Human
Immunogen aa. 114-132 (KYYFRGDLGGYNQYTFSEH)
(100% homologous in Human, Mouse and Rat).
Conjugation Un-conjugated
Alternate Names GMA; Myelin-associated glycoprotein; SIGLEC4A; S-MAG; Siglec-4a; SIGLEC-4A

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1 - 5 µg/ml
WB0.5 - 1 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.025% Sodium azide and 2.5% BSA.
Preservative 0.025% Sodium azide
Stabilizer 2.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17136 Mouse MAG

GeneID: 29409 Rat MAG

GeneID: 4099 Human MAG

Gene Symbol MAG
Gene Full Name myelin associated glycoprotein
Background The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]
Function Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). [UniProt]
Calculated MW 60-100 kDa (glycosylated)
PTM N-glycosylated.
Phosphorylated on tyrosine residues.