ARG59856
anti-MAN1A2 antibody
anti-MAN1A2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MAN1A2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MAN1A2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 60-180 of Human MAN1A2 (NP_006690.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Mannosidase alpha class 1A member 2; MAN1B; Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Alpha-1,2-mannosidase IB; EC 3.2.1.113; Processing alpha-1,2-mannosidase IB |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Mouse liver and A-549 | ||||||
| Observed Size | 80 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O60476 Human Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB Swiss-port # P39098 Mouse Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB |
|---|---|
| Gene Symbol | MAN1A2 |
| Gene Full Name | mannosidase, alpha, class 1A, member 2 |
| Background | Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information.[supplied by OMIM, Mar 2008] |
| Function | Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). [UniProt] |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein. [UniProt] |
| Calculated MW | 73 kDa |
