ARG40452
anti-ME2 antibody
anti-ME2 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ME2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ME2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 220-479 of Human ME2 (NP_001161807.1). |
| Conjugation | Un-conjugated |
| Alternate Names | NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; Malic enzyme 2; EC 1.1.1.38 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | LO2 | ||||
| Observed Size | 65 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P23368 Human NAD-dependent malic enzyme, mitochondrial |
|---|---|
| Gene Symbol | ME2 |
| Gene Full Name | malic enzyme 2, NAD(+)-dependent, mitochondrial |
| Background | This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009] |
| Cellular Localization | Mitochondrion matrix. [UniProt] |
| Calculated MW | 65 kDa |
