ARG44121
anti-MECR antibody
anti-MECR antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal recognizes MECR |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MECR |
| Antigen Species | Human |
| Immunogen | Human MECR recombinant protein (Position: E39-A359). |
| Conjugation | Un-conjugated |
| Alternate Names | MECR; Mitochondrial Trans-2-Enoyl-CoA Reductase; CGI-63; FASN2B; NRBF1; ETR1; Enoyl-[Acyl-Carrier-Protein] Reductase, Mitochondrial; Mitochondrial 2-Enoyl Thioester Reductase; Nuclear Receptor Binding Factor 1; 2-Enoyl Thioester Reductase; Homolog Of Yeast 2-Enoyl Thioester Reductase; Trans-2-Enoyl-CoA Reductase, Mitochondrial; Nuclear Receptor-Binding Factor 1; EC 1.3.1.104; EC 1.3.1.38; HsNrbf-1; DYTOABG; NRBF-1; NBRF1 |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MECR |
| Gene Full Name | Mitochondrial Trans-2-Enoyl-CoA Reductase |
| Background | The protein encoded by this gene is an oxidoreductase that catalyzes the last step in mitochondrial fatty acid synthesis. Defects in this gene are a cause of childhood-onset dystonia and optic atrophy. |
| Function | Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Displays a preference for medium-chain over short- and long-chain substrates. |
| Cellular Localization | Cytoplasm, Mitochondrion, Nucleus |
| Calculated MW | 40 kDa |
| PTM | Acetylation |
