ARG41159
anti-MEOX1 / MOX1 antibody
anti-MEOX1 / MOX1 antibody for ChIP,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MEOX1 / MOX1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ChIP, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MEOX1 / MOX1 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 7-38 of Human MOX1. |
| Conjugation | Un-conjugated |
| Alternate Names | Homeobox protein MOX-1; Mesenchyme homeobox 1; KFS2; MOX1 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | 293 | ||||||||
| Observed Size | 28 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MEOX1 |
| Gene Full Name | mesenchyme homeobox 1 |
| Background | This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Function | Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm. Note=Localizes predominantly in the nucleus. [UniProt] |
| Calculated MW | 28 kDa |
