ARG63791

anti-MEPI / SERPINI2 antibody

anti-MEPI / SERPINI2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cell Biology and Cellular Response antibody

Overview

Product Description Goat Polyclonal antibody recognizes MEPI / SERPINI2
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application IHC-P, WB
Specificity This antibody is expected to recognise both reported isoforms (NP_006208.1; NP_001012303.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name MEPI / SERPINI2
Antigen Species Human
Immunogen C-KGDWKQKFRKEDTQ
Conjugation Un-conjugated
Alternate Names TSA2004; Myoepithelium-derived serine protease inhibitor; Peptidase inhibitor 14; Serpin I2; PANCPIN; MEPI; Pancpin; PI-14; Pancreas-specific protein TSA2004; PI14

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 µg/ml
WB0.3 - 1 µg/ml
Application Note IHC-P: Antigen Retrieval: Microwaved tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5276 Human SERPINI2

Swiss-port # O75830 Human Serpin I2

Background The protein encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Area Cell Biology and Cellular Response antibody
Calculated MW 46 kDa