ARG40444
anti-MFI2 / Melanotransferrin antibody
anti-MFI2 / Melanotransferrin antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MFI2 / Melanotransferrin |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MFI2 / Melanotransferrin |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 20-200 of Human MFI2 / Melanotransferrin (NP_201573.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Melanoma-associated antigen p97; MTF1; CD antigen CD228; MAP97; Melanotransferrin; CD228; MTf |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | SW480 | ||||
| Observed Size | 110 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MFI2 |
| Gene Full Name | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| Background | The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008] |
| Function | Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. [UniProt] |
| Cellular Localization | Isoform 1: Cell membrane; Lipid-anchor, GPI-anchor. [UniProt] |
| Calculated MW | 80 kDa |
