ARG44195
anti-MISP antibody
anti-MISP antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MISP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MISP |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human MISP |
| Conjugation | Un-conjugated |
| Protein Full Name | Mitotic interactor and substrate of PLK1 |
| Alternate Names | MISP; Mitotic Spindle Positioning; C19orf21; Caprice; MISP1; Mitotic Interactor And Substrate Of Plk1; Mitotic Interactor And Substrate Of PLK1; Mitotic Spindle Positioning Protein; DKFZp686H18209; Chromosome 19 Open Reading Frame 21 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8IVT2 Human Mitotic interactor and substrate of PLK1 |
|---|---|
| Gene Symbol | MISP |
| Gene Full Name | Mitotic Spindle Positioning |
| Background | The protein encoded by this gene is an actin-bundling protein involved in determining cell morphology and mitotic progression. The encoded protein is required for the proper positioning of the mitotic spindle. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. |
| Function | Plays a role in mitotic spindle orientation and mitotic progression. Regulates the distribution of dynactin at the cell cortex in a PLK1-dependent manner, thus stabilizing cortical and astral microtubule attachments required for proper mitotic spindle positioning. May link microtubules to the actin cytospkeleton and focal adhesions. May be required for directed cell migration and centrosome orientation. May also be necessary for proper stacking of the Golgi apparatus. |
| Cellular Localization | Cell junction, Cytoplasm, Cytoskeleton |
| Calculated MW | 75 kDa |
| PTM | Phosphoprotein |
