ARG44353
anti-MKL2 antibody
anti-MKL2 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MKL2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MKL2 |
| Antigen Species | Human |
| Immunogen | Human MKL2 recombinant fusion protein (a.a. sequence: 170-300). |
| Conjugation | Un-conjugated |
| Alternate Names | MRTFB; Myocardin Related Transcription Factor B; MRTF-B ; MKL2; Myocardin-Related Transcription Factor B; MKL And Myocardin Family Member 2; MKL/Myocardin-Like Protein 2; Megakaryoblastic Leukemia 2; MKL1/Myocardin Like 2; MKL/Myocardin Like 2; FLJ31823; CTA-276F8.1; KIAA1243; NPD001 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.01% Thimerosal and 50% Glycerol. |
| Preservative | 0.01% Thimerosal |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MRTFB |
| Gene Full Name | Myocardin Related Transcription Factor B |
| Background | Enables transcription coactivator activity. Involved in positive regulation of pri-miRNA transcription by RNA polymerase II and positive regulation of striated muscle tissue development. Predicted to be located in cytoplasm. Predicted to be active in nucleus. |
| Function | Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation. |
| Cellular Localization | Nucleus |
| Calculated MW | 118 kDa |
| PTM | Glycoprotein, Isopeptide bond, Phosphoprotein, Ubl conjugation |
