ARG42157
anti-MLC1 antibody
anti-MLC1 antibody for ICC/IF,Western blot and Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MLC1 |
|---|---|
| Tested Reactivity | Rat |
| Predict Reactivity | Ms, Cow, Dog, Gpig, Hrs, Rb |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MLC1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the middle region of Human MLC1. (within the following region: SDSAN ILDEV PFPAR VLKSY SVVEV IAGIS AVLGG IIALN VDDSV SGPHL) |
| Conjugation | Un-conjugated |
| Alternate Names | LVM; MLC; VL; Membrane protein MLC1 |
Application Instructions
| Predict Reactivity Note | Predicted Homology Based on Immunogen Sequence: Cow: 91%; Dog: 86%; Guinea pig: 92%; Horse: 86%; Mouse: 93%; Rabbit: 83% | ||||||
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| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| Preservative | 0.09% (w/v) Sodium azide |
| Stabilizer | 2% Sucrose |
| Concentration | Batch dependent: 0.5 - 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | MLC1 |
|---|---|
| Gene Full Name | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| Background | The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Function | Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. [UniProt] |
| Cellular Localization | Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum. [UniProt] |
| Calculated MW | 41 kDa |
