ARG66363
anti-MMP15 antibody
anti-MMP15 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MMP15 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MMP15 |
| Antigen Species | Human |
| Immunogen | Fusion protein of Human MMP15. |
| Conjugation | Un-conjugated |
| Alternate Names | MT-MMP 2; Membrane-type matrix metalloproteinase 2; SMCP-2; MT2MMP; EC 3.4.24.-; Membrane-type-2 matrix metalloproteinase; MT2-MMP; MTMMP2; Matrix metalloproteinase-15; MMP-15 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse stomach, heart and liver tissue, HT-29 cells. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 40% Glycerol |
| Concentration | 0.6 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MMP15 |
| Gene Full Name | matrix metallopeptidase 15 (membrane-inserted) |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008] |
| Function | Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. [UniProt] |
| Calculated MW | 76 kDa |
| PTM | The precursor is cleaved by a furin endopeptidase. [UniProt] |
