ARG55535

anti-MMP9 antibody [S51-82]

anti-MMP9 antibody [S51-82] for Immunohistochemistry,Western blot and Human,Mouse,Rat

Brain Injury IHC Study antibody

Overview

Product Description

Mouse Monoclonal antibody [S51-82] recognizes MMP9

Tested Reactivity Hu, Ms, Rat
Tested Application IHC, WB
Host Mouse
Clonality Monoclonal
Clone S51-82
Isotype IgG2a
Target Name MMP9
Antigen Species Rat
Immunogen Fusion protein (full-length) of Rat MMP9 (NP_112317.1).
Conjugation Un-conjugated
Alternate Names Matrix metalloproteinase-9; MMP-9; Gelatinase B; GELB; 92 kDa gelatinase; EC 3.4.24.35; 92 kDa type IV collagenase

Application Instructions

Application Suggestion
Tested Application Dilution
IHC1 - 5 µg/ml
WB1 - 2 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol
Preservative 0.09% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17395 Mouse MMP9

GeneID: 4318 Human MMP9

GeneID: 81687 Rat MMP9

Gene Symbol Mmp9
Gene Full Name matrix metallopeptidase 9
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Function Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity). [UniProt]
Highlight Related products:
MMP9 antibodies; MMP9 ELISA Kits; MMP9 Duos / Panels; Anti-Mouse IgG secondary antibodies;
Related news:
Rat MMP9 ELISA Kit is available in arigo 
Research Area Brain Injury IHC Study antibody
Calculated MW 78 kDa
PTM Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9.
N- and O-glycosylated.