ARG41835

anti-MOG / Myelin oligodendrocyte glycoprotein antibody

anti-MOG / Myelin oligodendrocyte glycoprotein antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes MOG / Myelin oligodendrocyte glycoprotein
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MOG / Myelin oligodendrocyte glycoprotein
Antigen Species Human
Immunogen Synthetic peptide of Human MOG / Myelin oligodendrocyte glycoprotein.
Conjugation Un-conjugated
Alternate Names BTNL11; BTN6; NRCLP7; MOGIG2; Myelin-oligodendrocyte glycoprotein

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:500
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse brain
Observed Size ~ 28 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17441 Mouse MOG

GeneID: 24558 Rat MOG

GeneID: 4340 Human MOG

Gene Symbol MOG
Gene Full Name myelin oligodendrocyte glycoprotein
Background The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Function Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. [UniProt]
Cellular Localization Isoform 1 and 5: Cell membrane; Multi-pass membrane protein. Isoform 2, 3, 4, 6, 7, 8, and 9: Cell membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 28 kDa