ARG23237

anti-MPO / Myeloperoxidase antibody [2C7] (FITC)

anti-MPO / Myeloperoxidase antibody [2C7] (FITC) for Flow cytometry and Human

Inflammatory Cell Marker antibody; Neurophil Marker antibody

Overview

Product Description FITC-conjugated Mouse Monoclonal antibody [2C7] recognizes MPO / Myeloperoxidase
Tested Reactivity Hu
Species Does Not React With Rat
Tested Application FACS
Host Mouse
Clonality Monoclonal
Clone 2C7
Isotype IgG1
Target Name MPO / Myeloperoxidase
Antigen Species Human
Immunogen Human myeloperoxidase.
Conjugation FITC
Alternate Names MPO; Myeloperoxidase; EC 1.11.2.2

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:50 - 1:100
Application Note FACS: Membrane permeabilisation is required for this application. Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.09% Sodium azide and 1% BSA.
Preservative 0.09% Sodium azide
Stabilizer 1% BSA
Concentration 0.1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4353 Human MPO

Swiss-port # P05164 Human Myeloperoxidase

Gene Symbol MPO
Gene Full Name myeloperoxidase
Background Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
Function Myeloperoxidase (MPO): Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt]
Highlight Related products:
MPO antibodies; MPO ELISA Kits; MPO Duos / Panels; Anti-Mouse IgG secondary antibodies;
Related news:
Exploring Antiviral Immune Response
Research Area Inflammatory Cell Marker antibody; Neurophil Marker antibody
Calculated MW 84 kDa