ARG66954
anti-MPO / Myeloperoxidase antibody
anti-MPO / Myeloperoxidase antibody for IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
Inflammatory Cell Marker antibody; Neurophil Marker antibody
Overview
| Product Description | Mouse Polyclonal antibody recognizes MPO / Myeloperoxidase |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MPO / Myeloperoxidase |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human MPO / Myeloperoxidase. |
| Conjugation | Un-conjugated |
| Protein Full Name | Myeloperoxidase |
| Alternate Names | MPO; Myeloperoxidase; EC 1.11.2.2; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Human Lung |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MPO |
| Gene Full Name | myeloperoxidase |
| Background | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014] |
| Function | Myeloperoxidase (MPO): Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt] |
| Cellular Localization | Lysosome. [UniProt] |
| Highlight | Related Antibody Duos and Panels: ARG30325 Inflammatory Cell Antibody Panel Related products: MPO antibodies; MPO ELISA Kits; MPO Duos / Panels; Anti-Mouse IgG secondary antibodies; Related news: Exploring Antiviral Immune Response |
| Research Area | Inflammatory Cell Marker antibody; Neurophil Marker antibody |
| Calculated MW | 60 kDa, 84 kDa, 89 kDa |
