ARG44206
anti-MPZL1 antibody
anti-MPZL1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MPZL1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MPZL1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human MPZL1 |
| Conjugation | Un-conjugated |
| Protein Full Name | Myelin protein zero-like protein 1 |
| Alternate Names | GeneCards Symbol: MPZL1; Myelin Protein Zero Like 1; PZR; Myelin Protein Zero-Like Protein 1; FLJ21047; Immunoglobulin Family Transmembrane Protein; Protein Zero Related; Protein Zero-Related; MPZL1b; PZR1b; PZRa; PZRb |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O95297 Human Myelin protein zero-like protein 1 |
|---|---|
| Gene Symbol | MPZL1 |
| Gene Full Name | Myelin Protein Zero Like 1 |
| Background | Predicted to enable structural molecule activity. Predicted to be involved in cell-cell signaling and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within positive regulation of cell migration. Located in cell surface and focal adhesion. |
| Function | Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility. |
| Cellular Localization | Membrane |
| Calculated MW | 29 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein |
