ARG40472

anti-MSRA antibody

anti-MSRA antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes MSRA
Tested Reactivity Hu, Ms
Predict Reactivity Bov
Tested Application FACS, ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MSRA
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 34-63 of Human MSRA.
Conjugation Un-conjugated
Alternate Names EC 1.8.4.11; Peptide Met; O; Peptide-methionine; Protein-methionine-S-oxide reductase; Mitochondrial peptide methionine sulfoxide reductase; S; PMSR

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:10 - 1:50
ICC/IF1:100
IHC-P1:10 - 1:50
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human kidney
Observed Size ~ 26 kDa

Properties

Form Liquid
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 110265 Mouse MSRA

GeneID: 4482 Human MSRA

Swiss-port # Q9D6Y7 Mouse Mitochondrial peptide methionine sulfoxide reductase

Swiss-port # Q9UJ68 Human Mitochondrial peptide methionine sulfoxide reductase

Gene Symbol MSRA
Gene Full Name methionine sulfoxide reductase A
Background This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Function Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. [UniProt]
Cellular Localization Isoform 1: Mitochondrion. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm. Nucleus. Isoform 5: Cytoplasm. Membrane; Lipid-anchor. [UniProt]
Calculated MW 26 kDa