ARG43601

anti-MTCO1 antibody

anti-MTCO1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunocytochemistry,Western blot and Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes MTCO1
Tested Reactivity Ms, Rat
Tested Application ICC, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MTCO1
Antigen Species Mouse
Immunogen Synthetic peptide corresponding to a sequence at the C-terminus of Human MTCO1(501-514aa PYHTFEEPVYMKS).
Conjugation Un-conjugated
Protein Full Name Cytochrome c oxidase subunit 1
Alternate Names Cytochrome c oxidase subunit 1; EC 1.9.3.1; COX1; Cytochrome c oxidase polypeptide I; MTCO1; COI

Application Instructions

Application Suggestion
Tested Application Dilution
ICC0.5 - 1 µg/ml
IHC-P0.5 - 1 µg/ml
WB0.1 - 0.5 µg/ml
Application Note IHC-P: Antigen Retrieval: By heat mediation.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse heart, Rat brain, Hepa 1-6
Observed Size 37 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
Preservative 0.05% Thimerosal and 0.05% Sodium azide
Stabilizer 5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17708 Mouse MT-CO1

GeneID: 26195 Rat MT-CO1

Swiss-port # P00397 Mouse Cytochrome c oxidase subunit 1

Swiss-port # P05503 Rat Cytochrome c oxidase subunit 1

Gene Symbol MT-CO1
Gene Full Name mitochondrially encoded cytochrome c oxidase I
Function Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. [UniProt]
Cellular Localization Mitochondrion inner membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 57 kDa