ARG42216

anti-MTHFD1L antibody

anti-MTHFD1L antibody for Western blot,ICC/IF and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes MTHFD1L
Tested Reactivity Hu
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MTHFD1L
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 759-978 of Human MTHFD1L (NP_056255.2).
Conjugation Un-conjugated
Alternate Names MTC1THFS; dJ292B18.2; Formyltetrahydrofolate synthetase; EC 6.3.4.3; Monofunctional C1-tetrahydrofolate synthase, mitochondrial; FTHFSDC1

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:100
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control A549
Observed Size ~ 117 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 25902 Human MTHFD1L

Swiss-port # Q6UB35 Human Monofunctional C1-tetrahydrofolate synthase, mitochondrial

Gene Symbol MTHFD1L
Gene Full Name methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Background The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Function May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2. [UniProt]
Cellular Localization Mitochondrion. [UniProt]
Calculated MW 106 kDa