ARG64111

anti-MUTYH antibody

anti-MUTYH antibody for Western blot and Human

Gene Regulation antibody

Overview

Product Description Goat Polyclonal antibody recognizes MUTYH
Tested Reactivity Hu
Tested Application WB
Specificity This antibody is expected to recognise all reported isoforms (NP_036354.1; NP_001041636.1; NP_001041637.1; NP_001041638.1; NP_001121897.1). Reported variants represent identical protein (NP_001041638.1; NP_001041639.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name MUTYH
Antigen Species Human
Immunogen C-HISTDAHSLNSAAQ
Conjugation Un-conjugated
Alternate Names MYH; A/G-specific adenine DNA glycosylase; MutY homolog; hMYH; EC 3.2.2.-

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.1 - 0.3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4595 Human MUTYH

Swiss-port # Q9UIF7 Human A/G-specific adenine DNA glycosylase

Background This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Area Gene Regulation antibody
Calculated MW 60 kDa