ARG40447
anti-MYH1 antibody
anti-MYH1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MYH1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Specificity | The antibody might also react to MYH4 (95%), MYH2 (90%) and MTH8 (85%) based on sequence homology analysis. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MYH1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-100 of Human MYH1 (NP_005954.3). |
| Conjugation | Un-conjugated |
| Alternate Names | Myosin heavy chain IIx/d; MYHa; HEL71; MyHC-IIx/d; Myosin heavy chain 1; MyHC-2x; MyHC-2X/D; Myosin heavy chain, skeletal muscle, adult 1; Myosin heavy chain 2x; Myosin-1; MYHSA1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Mouse heart | ||||||||
| Observed Size | 260 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MYH1 |
| Gene Full Name | myosin, heavy chain 1, skeletal muscle, adult |
| Background | Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008] |
| Function | Muscle contraction. [UniProt] |
| Cellular Localization | Cytoplasm, myofibril. Note=Thick filaments of the myofibrils. [UniProt] |
| Calculated MW | 223 kDa |
