ARG40487
anti-MYH3 antibody
anti-MYH3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MYH3 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Specificity | This antibody is human, mouse and rat reactive. The antibody is predicted to not cross-react with other members of the myosin heavy chain family. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MYH3 |
| Antigen Species | Human |
| Immunogen | 19 aa (N-terminus) of Human MYH3. |
| Conjugation | Un-conjugated |
| Alternate Names | Myosin heavy chain 3; MYHSE1; Myosin heavy chain, fast skeletal muscle, embryonic; Muscle embryonic myosin heavy chain; HEMHC; MYHC-EMB; Myosin-3; SMHCE |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Jurkat |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MYH3 |
| Gene Full Name | myosin, heavy chain 3, skeletal muscle, embryonic |
| Background | Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes, Freeman-Sheldon syndrome and Sheldon-Hall syndrome. [provided by RefSeq, Jul 2008] |
| Function | Muscle contraction. [UniProt] |
| Cellular Localization | Cytoplasm, myofibril. Note=Thick filaments of the myofibrils. [UniProt] |
| Calculated MW | 224 kDa |
